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I/L Determination in De Novo Antibody Sequencing

I/L Determination in De Novo Antibody Sequencing

I/L Determination in De Novo Antibody Sequencing Isoleucine and leucine determination De novo antibody sequencing by tandem mass spectrometry(MS/MS) uses the differences in mass of different amino acids to accurately determine the correct sequence. Distinguishing...
Constructing an Accurate Antibody Repertoire

Constructing an Accurate Antibody Repertoire

Constructing an Accurate Antibody Repertoire What is an antibody repertoire? The immune repertoire is the collection of unique immunoglobulin and T-cell receptor sequences present in an individual at a particular time. At Digital Proteomics we focus primarily on the...
From RNA to Sequencing: QC Matters

From RNA to Sequencing: QC Matters

From RNA to Sequencing: QC Matters Sequencing the immunoglobulin (Ig) repertoire provides us with important information on the adaptive immune response, and can help with the development of diagnostic and therapeutic applications. A single human can have an estimated...
De Novo Antibody Sequencing Process: An Overview

De Novo Antibody Sequencing Process: An Overview

De Novo Antibody Sequencing Process: An Overview If you search the internet for ‘antibody sequencing’, you will be rewarded with a long list of resources and services. The terms used to describe antibody sequencing are overloaded and highly similar. We felt a single...
Our Alicanto Approach to Antibody Discovery

Our Alicanto Approach to Antibody Discovery

Our Alicanto Approach to Antibody Discovery Why antibody discovery from serum? We recently launched our Alicanto® antibody discovery service. Since then we’ve fielded many inquiries about how our approach is different than traditional antibody discovery approaches. ...