888-416-9305 info@abterrabio.com


employment opportunities

Ready to join our team and make a difference?

Abterra Biosciences is a growing biotechnology startup developing a novel platform for mining the natural immune response for the next-generation of antibody therapeutics. Abterra Biosciences utilizes next-generation sequencing to decode the cellular antibody repertoire and the latest proteomics techniques to analyze the functional serum repertoire. We are a multi-disciplinary team seeking individuals that want to develop new tools to unlock the immune system.

Open Positions

Please send your CV or resume to hiring@abterrabio.com

Senior Analytical Chemist - San Diego, CA


  • Operate and maintain nano-flow liquid chromatography and high-resolution mass spectrometry (nano-LC-HRMS) instrumentation.
  • Develop and validate of tandem MS-based analytical methods and standard operating procedures (SOPs) for discovery and targeted proteomics of complex antibody samples.
  • Develop SOPs for LC-MS maintenance, operation and troubleshooting in a production setting.
  • Collaborate with bioinformaticians and biologists to achieve technology milestones.
  • Stay up to date on relevant literature in protein mass spectrometry, antibody discovery, and related areas.
  • Communicate methods and results in presentations, publications, and posters.
  • Contribute to our intellectual property portfolio.

Required Skills:

  • PhD in chemistry, biochemistry, or similar with 3+ years of post-graduate work in academia or industry.
  • Experience designing and implementing in-solution and in-gel digestion approaches to enable workflows for discovery proteomics.
  • Strong analytical and practical skills in protein sample preparation and nano-LC-HRMS for proteomic analysis.
  • Experience with Orbitrap type instrumentation and in-depth knowledge of instrument calibration, operation, troubleshooting, and maintenance (i.e. Q-Exactive, Orbitrap Fusion Lumos, Orbitrap Eclipse).
  • Experience with various standard in-solution and in-gel proteomic sample prep protocols for bottom-up proteomic workflows.
  • Ability to pick up new technologies quickly and troubleshoot independently.
  • Proven track record of independent critical thinking, scientific achievement, and the ability to interact creatively and collaboratively with relevant departments.


Desired Skills:

  • Experience with handling human as well as animal biomatrices (plasma/serum).
  • Excellent analytical chemistry skills with a working knowledge and hands-on experience developing bottom-up and top/middle-down proteomic workflows using nano-flow LC-MS systems.
  • Experience with labeled (TMT or iTRAQ) and label-free quantitative proteomic approaches (i.e. data-independent acquisition).
  • Experience with data analysis software platforms, as well as third-party software platforms such as Max Quant, Trans-Proteomic Pipeline, Skyline, and Scaffold.
  • Expertise with FPLC protein purification techniques such as IMAC, SEC, IEX, HIC.
  • Expertise in preparing samples and performing liquid chromatography fractionation.
  • Experience with high-throughput quantitative proteomic approaches; including sample multiplexing and modern liquid chromatography fractionation techniques.


  • Competitive health and dental plans
  • Employer retirement plan
  • Flexible vacation
  • On-site gym access
Research Associate - San Diego, CA


  • Conduct lab work under the general direction of your supervisor.
  • Recognize potential problems in order to understand and troubleshoot assays.
  • Communicate clearly through an electronic lab notebook the protocols used and experimental results.
  • Maintain an organized lab and work space.
  • Collaborate with assay development scientists, bioinformatics scientists, and vendors to optimize and automate workflows.

Required Qualifications:

  • B.S. in biochemistry, biology, genomics or similar field.
  • 0-2 years post-undergraduate experience in life sciences.
  • Experience with molecular biology techniques including RNA extraction, cDNA synthesis, PCR, and gel electrophoresis.
  • Flexibility and curiosity to learn new techniques and workflows.

Preferred Qualification:

  • Experience with preparing libraries for the Illumina MiSeq system.
  • Experience in protein expression.
  • Experience in protein chemistry and purification.
  • Experience with Good Laboratory Practices.


  • Competitive health and dental plans
  • Employer retirement plan
  • Flexible vacation
  • On-site gym access

Perks & Benefits


Employer Retirement Plan

Flexible Work Schedule

Competitive Health and Dental Plans

Flexible Time Off

Paid Parental Leave

Targeted Bonus Program

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