Jul 14, 2026 | Science, Services
Hybridoma Sequencing Pitfalls: 3 Top Lessons Learned Motivation Since the technology’s invention in 1975, hybridomas have been a favored method of monoclonal antibody production. By fusing immortal myeloma cells with antibody producing B cells in culture,...
Jun 4, 2026 | Science, Services
Human Antibody Sequencing from Serum Motivation Human antibody sequencing is a powerful tool for understanding the humoral immune response. Until recently, B cell-focused approaches have been the only available tool for understanding the diversity and plasticity of...
Apr 27, 2026 | News, Science, Services
De Novo Antibody Sequencing: Which Enzymes are Best? De novo antibody sequencing is the process of determining the primary amino acid sequence of an antibody directly from the protein. Determining the sequence of an antibody is a requirement for many downstream...
Dec 19, 2025 | Products, Science, Services
Can You Sequence an Antibody? What does it mean to sequence an antibody? Antibodies are tetrameric proteins comprised of two identical heavy chains and two identical light chains. One naturally occurring exception to this is the heavy chain-only antibodies produced by...
Nov 23, 2025 | Science, Services
FASTA2AIRR: comparing human and humanized antibodies Fasta2airr is a free web app for converting antibody sequences into annotated AIRR-Seq files. Converting sequences into this open format is an essential step in antibody repertoire analysis. Among other antibody...
Sep 17, 2025 | News, Science, Services
VHH De Novo Antibody Sequencing VHHs are 15kDa proteins that represent the antigen binding portion of heavy chain-only antibodies (HCAb) from llamas and alpacas. Their small size and stability make them ideal components of therapeutics such as bispecific antibodies or...
