In recent years, camelids have become more than hearty travel companions due to their unconventional adaptive immune systems. Conventional IgG antibodies are tetrameric molecules comprised of two heavy chains and two light chains with molecular weights of roughly ~150...
What is an antibody repertoire?The immune repertoire is the collection of unique immunoglobulin and T-cell receptor sequences present in an individual at a particular time. At Digital Proteomics we focus primarily on the immunoglobulin, or B-cell receptor repertoires...
Sequencing the immunoglobulin (Ig) repertoire provides us with important information on the adaptive immune response, and can help with the development of diagnostic and therapeutic applications. A single human can have an estimated 10¹¹ B cells with millions of...
If you search the internet for ‘antibody sequencing’, you will be rewarded with a long list of resources and services. The terms used to describe antibody sequencing are overloaded and highly similar. We felt a single resource that explained the why and how of the de...
Why antibody discovery from serum?We recently launched our Alicanto® antibody discovery service. Since then we’ve fielded many inquiries about how our approach is different than traditional antibody discovery approaches. Our response is simple: we trust the immune...
Shedding light on the spectacular world of small molecules! Spectral libraries contain only a tiny fraction of the diverse universe of metabolites observed in biological samples. Molecular networking provides a rich visualization tool to organize families of related...
