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Scientific News

Case Study: Reptor Phage Enrichment

Case Study: Reptor Phage Enrichment

Case Study: Phage EnrichmentProject Summary: Phage display is a powerful toolkit for antibody discovery and engineering. In this study, we used phage display to identify Cas9-binding single domain (VHH) antibodies. In addition to traditional colony picking, we used...

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Why Sequence My Antibody Protein?

Why Sequence My Antibody Protein?

Over the past decade of sequencing thousands of antibodies, we've discovered the top reasons to sequence your antibody protein.Top reasons to sequence my antibody  1. To protect my intellectual property through patents for regulatory application and antibody...

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Customer Spotlight: Dr. Matthew Burchill

Customer Spotlight: Dr. Matthew Burchill

Valens™ Rescues Antibody for Liver Disease ResearchDr. Matthew Burchill explains how Abterra Bio's technology, Valens  rescued his antibody and enabled him to continue his research in chronic liver disease. "The sequencing provided is instrumental to our work as the...

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Multi-Species Antibody Repertoire Comparison

Multi-Species Antibody Repertoire Comparison

A decade ago, in vivo antibody discovery relied heavily on wild-type mice. Today, it’s not uncommon to generate antibodies using a petting zoo of animals including chicken, goat, rabbit, llamas, alpacas, and humanized rodents. The immune responses of these animals...

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NGS During The Hybridoma Generation Process

NGS During The Hybridoma Generation Process

Next-generation sequencing (NGS) has allowed for unprecedented insights into patterns of the immune response. It can enable high-throughput sequencing of hybridomas as we have discussed in NGS-Enhanced antibody discovery blog post and resource pages. NGS can provide a...

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De Novo Antibody Sequencing Case Study

De Novo Antibody Sequencing Case Study

Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and...

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