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Scientific News

Customer Spotlight: Dr. Matthew Burchill

Customer Spotlight: Dr. Matthew Burchill

Valens™ Rescues Antibody for Liver Disease ResearchDr. Matthew Burchill explains how Abterra Bio's technology, Valens  rescued his antibody and enabled him to continue his research in chronic liver disease. "The sequencing provided is instrumental to our work as the...

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Multi-Species Antibody Repertoire Comparison

Multi-Species Antibody Repertoire Comparison

A decade ago, in vivo antibody discovery relied heavily on wild-type mice. Today, it’s not uncommon to generate antibodies using a petting zoo of animals including chicken, goat, rabbit, llamas, alpacas, and humanized rodents. The immune responses of these animals...

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NGS During The Hybridoma Generation Process

NGS During The Hybridoma Generation Process

Next-generation sequencing (NGS) has allowed for unprecedented insights into patterns of the immune response. It can enable high-throughput sequencing of hybridomas as we have discussed in NGS-Enhanced antibody discovery blog post and resource pages. NGS can provide a...

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De Novo Antibody Sequencing Case Study

De Novo Antibody Sequencing Case Study

Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and...

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Immune Repertoire Sequencing in Human

Immune Repertoire Sequencing in Human

Immune repertoire sequencing enables deeper understanding of the adaptive immune response [1].  Abterra Biosciences has developed Reptor™, a flexible immune repertoire sequencing and analysis service. In this study, we analyzed the B-cell receptor (BCR) repertoire...

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Clonal Hit-Expansion Case Study

Clonal Hit-Expansion Case Study

Abterra Bio uses next-generation sequencing to mine the clonal lineage of serum-identified antibodies. This method rescues relatives of hits that are within a clone and increases diversity in your antibody discovery campaign.  Contact us to learn more about how our...

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Llama Immune Repertoire Profiling

Llama Immune Repertoire Profiling

Alicanto® is Abterra Biosciences' proprietary antibody discovery platform that mines the entire immune response to identify diverse, functional antibodies. For an overview of the proteogenomic process, read more about Alicanto®. The infographic below was created using...

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