888-416-9305 info@abterrabio.com

Griffin: Accessing functional antibodies from serum without B cells

May 20, 2025 | Science, Services

Griffin is a platform for sequencing polyclonal antibodies using mass spectrometry.  Since 2009, Abterra Biosciences founders and employees have been developing novel methods for sequencing antibody proteins directly.  Our monoclonal antibody sequencing service, Valens, has been used to successfully sequence hundreds of antibodies without the need for B cells.  Now, with Griffin, we can sequencing complex mixes of antibodies directly from patient serum, or from immunized animals.

Watch our CEO, Dr. Natalie Castellana’s presentation on Unlocking the Serum Antibody Repertoire: Accessing Functional Antibodies without B Cells to learn how Griffin works.

Click below to watch the presentation.

 

Related Posts

De Novo Antibody Sequencing Case Study

De Novo Antibody Sequencing Case Study

Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and...

A Decade of De Novo Antibody Sequencing Experience

A Decade of De Novo Antibody Sequencing Experience

De novo antibody sequencing experience Have you lost your hybridoma? Is your hybridoma no longer producing? Is your hybridoma producing more than your desired antibody? Do you have a monoclonal antibody from a clinical sample, but no way to recover the source B cell?...

Get In Touch

Tell Us About Your Project

Need more information? We’re here to answer any questions you have.