De Novo Antibody Sequencing Case Study
Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and isotype, including IgG’s and IgM’s.
Contact us to learn more about how our Valens™ de novo antibody sequencing can recover the full antibody sequence when no source cell is available!
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For 100% sequence accuracy, antibody sequencing experience matters. Read our blog post to understand more about our service and why you would need de novo sequencing.
De Novo Antibody Sequencing: Which Enzymes are Best?
De novo antibody sequencing is the process of determining the primary amino acid sequence of an antibody directly from the protein. Determining the sequence of an antibody is a requirement for many downstream activities. Intellectual Property Protection: In order to...
Can You Sequence an Antibody?
What does it mean to sequence an antibody?Antibodies are tetrameric proteins comprised of two identical heavy chains and two identical light chains. One naturally occurring exception to this is the heavy chain-only antibodies produced by camelids and cartilaginous...
FASTA2AIRR: comparing human and humanized antibodies
Fasta2airr is a free web app for converting antibody sequences into annotated AIRR-Seq files. Converting sequences into this open format is an essential step in antibody repertoire analysis. Among other antibody meta data the AIRR-Seq file contains: Germline gene...