A Decade of De Novo Antibody Sequencing Experience

De novo antibody sequencing experience

• Have you lost your hybridoma?
• Is your hybridoma no longer producing?
• Is your hybridoma producing more than your desired antibody?
• Do you have a monoclonal antibody from a clinical sample, but no way to recover the source B cell?

Valens™ is a de novo antibody sequencing service that reconstructs the full amino acid sequence of both antibody chains using bioinformatics and mass spectrometry. We perform sequencing using our in-house mass spectrometry lab, equipped with a state-of-the-art Thermo Fisher Orbitrap Eclipse instrument. 

For the past decade, we’ve been developing methods for sequencing monoclonal antibodies using proteomics. We wrote a blog post providing an overview of de novo antibody sequencing. For 100% sequence accuracy, antibody sequencing experience matters.