De Novo Antibody Sequencing Case Study
Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and isotype, including IgG’s and IgM’s.
Contact us to learn more about how our Valens™ de novo antibody sequencing can recover the full antibody sequence when no source cell is available!
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Related Resources
For 100% sequence accuracy, antibody sequencing experience matters. Read our blog post to understand more about our service and why you would need de novo sequencing.
Multi-Species Antibody Repertoire Comparison
Abterra Bio uses Reptor’s antibody repertoire analysis workflow to compare and visualize antibodies from both naïve and immunized animals.
NGS During The Hybridoma Generation Process
Next-generation sequencing (NGS) has allowed for unprecedented insights into patterns of the immune response. It can enable high-throughput sequencing of hybridomas as we have discussed in NGS-Enhanced antibody discovery blog post and resource pages. NGS can provide a...
A Decade of De Novo Antibody Sequencing Experience
De novo antibody sequencing experience Have you lost your hybridoma? Is your hybridoma no longer producing? Is your hybridoma producing more than your desired antibody? Do you have a monoclonal antibody from a clinical sample, but no way to recover the source B cell?...