Griffin: Accessing functional antibodies from serum without B cells
Griffin: Accessing functional antibodies from serum without B cells Griffin is a platform for sequencing polyclonal antibodies using mass spectrometry. Since 2009, Abterra Biosciences founders and employees have been developing novel methods for sequencing antibody...
Antibody Clonality Assessment
Antibody Clonality Assessment Antibody Clonality Background The serological compartment is simple to access and contains a multitude of proteins, a large fraction of which are circulating antibodies. At Abterra Bio, we developed Alicanto which utilizes B cells from a...
Unlocking the Secrets of SARS-CoV-2 Immunity: A Deep Dive into Serum Antibodies and B Cell Repertoires
Unlocking the Secrets of SARS-CoV-2 Immunity: A Deep Dive into Serum Antibodies and B Cell Repertoires Project Summary We’re excited to share our latest findings on the complex interplay between serum antibodies and B cell repertoires in individuals with...
VHH Discovery with Alicanto versus Phage Display
VHH Discovery with Alicanto versus Phage Display Project Summary Camelids such as llamas and alpacas produce conventional antibodies as well as heavy-chain only antibodies (HCAbs) from which the small, stable, antigen-binding domain (VHH) can be extracted....
Limit of Detection – Serum Antibody Analysis
In this blog post, we evaluate the limit of detection for serum antibody analysis achieved by Alicanto using spike ins.