Dec 19, 2025 | Products, Science, Services
Can You Sequence an Antibody? What does it mean to sequence an antibody? Antibodies are tetrameric proteins comprised of two identical heavy chains and two identical light chains. One naturally occurring exception to this is the heavy chain-only antibodies produced by...
Nov 23, 2025 | Science, Services
FASTA2AIRR: comparing human and humanized antibodies Fasta2airr is a free web app for converting antibody sequences into annotated AIRR-Seq files. Converting sequences into this open format is an essential step in antibody repertoire analysis. Among other antibody...
Sep 17, 2025 | News, Science, Services
VHH De Novo Antibody Sequencing VHHs are 15kDa proteins that represent the antigen binding portion of heavy chain-only antibodies (HCAb) from llamas and alpacas. Their small size and stability make them ideal components of therapeutics such as bispecific antibodies or...
Aug 19, 2025 | Science, Services
Polyclonal Antibody Sequencing in Camelids Serum contains circulating antibodies with unique functional properties. This fundamental fact is why we choose to mine the serum over cells – despite being more challenging. Here we compare the two approaches for...
Jul 25, 2025 | Products, Science, Services
Rabbit Polyclonal Antibody Sequencing for Neurodegenerative Disease Research Rabbit polyclonal antibodies are commonly used reagents across biotech and academia. As of 2024, 43% of commercial catalog antibodies are polyclonals, and 66% of those are rabbit derived....
Jun 26, 2025 | Science, Services
De Novo Antibody Sequencing NISTmAb with Post-Translational Modification Detection Protein sequencing has been possible for 75 years with Edman degradation, but over the past decade, mass spectrometry (MS)-based sequencing has become the dominant approach for...
