Sep 17, 2025 | News, Science, Services
VHH De Novo Antibody Sequencing VHHs are 15kDa proteins that represent the antigen binding portion of heavy chain-only antibodies (HCAb) from llamas and alpacas. Their small size and stability make them ideal components of therapeutics such as bispecific antibodies or...
Aug 19, 2025 | Science, Services
Polyclonal Antibody Sequencing in Camelids Serum contains circulating antibodies with unique functional properties. This fundamental fact is why we choose to mine the serum over cells – despite being more challenging. Here we compare the two approaches for...
Jul 25, 2025 | Products, Science, Services
Rabbit Polyclonal Antibody Sequencing for Neurodegenerative Disease Research Rabbit polyclonal antibodies are commonly used reagents across biotech and academia. As of 2024, 43% of commercial catalog antibodies are polyclonals, and 66% of those are rabbit derived....
Jun 26, 2025 | Science, Services
De Novo Antibody Sequencing NISTmAb with Post-Translational Modification Detection Protein sequencing has been possible for 75 years with Edman degradation, but over the past decade, mass spectrometry (MS)-based sequencing has become the dominant approach for...
Jun 15, 2025 | Products, Science, Services
Monoclonal versus Polyclonal Antibody Sequencing Antibody reagents used in biomedical research and diagnostics assays fall into two large categories: monoclonals and polyclonals. For high-quality reagents, an antibody needs to demonstrate specific reactivity in its...
Jun 1, 2025 | Products, Science, Services
Polyclonal Antibody Sequencing Methods Polyclonal Antibody Sequencing Methods Polyclonal antibody sequencing is a powerful tool for understanding the humoral immune response.1 Two primary approaches exist: Proteogenomic Polyclonal Antibody Sequencing and De Novo...
