Griffin: Accessing functional antibodies from serum without B cells
Griffin is a platform for sequencing polyclonal antibodies using mass spectrometry. Since 2009, Abterra Biosciences founders and employees have been developing novel methods for sequencing antibody proteins directly. Our monoclonal antibody sequencing service, Valens, has been used to successfully sequence hundreds of antibodies without the need for B cells. Now, with Griffin, we can sequencing complex mixes of antibodies directly from patient serum, or from immunized animals.
Watch our CEO, Dr. Natalie Castellana’s presentation on Unlocking the Serum Antibody Repertoire: Accessing Functional Antibodies without B Cells to learn how Griffin works.
Click below to watch the presentation.
Related Posts
Limit of Detection – Serum Antibody Analysis
In this blog post, we evaluate the limit of detection for serum antibody analysis achieved by Alicanto using spike ins.
VHH Antibody Repertoire to Phage Library Comparison
We used Reptor to compare the VHH antibody repertoire from an immunized llama to a phage library constructed from the same source.
Case Study: Reptor Biological vs Technical Replicates
Replicates of immune repertoire sequencing projects can provide invaluable information about the total diversity of a sample.
Get In Touch


