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Abterra Biosciences discovers fully human antibodies from patients

Truly human antibody therapeutics.

Humans mount lasting antibody responses to infectious diseases and cancer. Abterra Bio uses next-generation sequencing, mass spectrometry, and machine learning to comprehensively map the antibody response, and rapidly identify better therapeutic antibodies. We’ve built an interdisciplinary team of data scientists and biologists to re-imagine how antibody therapeutics are developed.

Abterra Bio technology is built on decades of experience in antibody sequencing and analysis. Click on the services below to see how we can help you!

Abterra Bio Reptor Hybridoma Sequencing


Next-Gen Sequencing Hybridoma

Abterra Bio Reptor Bulk B Cell Sequencing


Next-Gen Sequencing Bulk B Cells
Abterra Bio Reptor Hit Expansion


Next-Gen Sequencing Hit Expansion 
Abterra Bio Reptor Library Sequencing


Next-Gen Sequencing Display Library
Abterra Bio Alicanto Rabbit Antibody Discovery


Rabbit Monoclonal Antibody Discovery
Abterra Bio Alicanto Single Domain Antibody Discovery


Single Domain (VHH) Antibody Discovery

Abterra Bio Alicanto Human Antibody Discovery


Human Antibody Discovery
Abterra Bio Valens Sequence Confirmation


Protein Sequence Confirmation
Abterra Bio Valens Antibody Protein Sequencing


Antibody Protein Sequencing

Our partners’ success means everything to us

I have had great experiences using Abterra Bio’s Reptor platform. The data generated was highly valuable, and the team provided quick and open communication throughout the whole process.

Sandeep Kumar, PhD

Associate Director - Antibody Discovery & Engineering, Scholar Rock

Latest News

PEGS Boston Summit 2021 Presentation

Abstract: Next-generation sequencing of antibody repertoires has provided new insights into natural immune responses.  The correlation between the B-cell receptor repertoire and the serological antibody repertoire has only been analyzed in a small number of studies. ...

Abterra Bio Seattle Angel Conference Winner

We’re excited to announce that Abterra Bio has been chosen as the Winner of the 19th Seattle Angel Conference and the Audience Favorite Award. This year, there were 81 start-up companies from all over the US that had applied. The selection process took around 2-3...

Digital Proteomics is Abterra Biosciences

We're excited to announce that Digital Proteomics is now Abterra Biosciences. Our vision for the business has evolved and it's time to realign our name with our capabilities; we have developed core technologies that are driving our partners' antibody discovery...

We are a CONNECT Cool Company 2021!

We’re excited to announce that Abterra Biosciences has been selected as "A Cool Company" for the second year in a row by CONNECT. CONNECT, a premier innovation company accelerator in San Diego that creates and scales great companies in the technology and life sciences...

Scientific Updates

NGS During The Hybridoma Generation Process

Next-generation sequencing (NGS) has allowed for unprecedented insights into patterns of the immune response. It can enable high-throughput sequencing of hybridomas as we have discussed in NGS-Enhanced antibody discovery blog post and resource pages. NGS can provide a...

De Novo Antibody Sequencing Case Study

Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and...

Immune Repertoire Sequencing in Human

Immune repertoire sequencing enables deeper understanding of the adaptive immune response [1].  Abterra Biosciences has developed Reptor™, a flexible immune repertoire sequencing and analysis service. In this study, we analyzed the B-cell receptor (BCR) repertoire...

Social Media Posts

The Abterra Bio team would like to wish you and your family a wonderful holiday season. We hope to work with you again in 2022!

With the use of NGS, our Reptor software was able to analyze the clone diversity during the hybridoma generation process, clone overlap across 3 bulk samples, and relatives of screened hits that can be used for hit expansion. Read our new blog post below!


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Every day, we strive to help our partners and collaborators push the boundaries of their science.

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