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FASTA2AIRR: comparing human and humanized antibodies

FASTA2AIRR: comparing human and humanized antibodies

FASTA2AIRR: comparing human and humanized antibodies Fasta2airr is a free web app for converting antibody sequences into annotated AIRR-Seq files. Converting sequences into this open format is an essential step in antibody repertoire analysis. Among other antibody...
VHH De Novo Antibody Sequencing

VHH De Novo Antibody Sequencing

VHH De Novo Antibody Sequencing VHHs are 15kDa proteins that represent the antigen binding portion of heavy chain-only antibodies (HCAb) from llamas and alpacas. Their small size and stability make them ideal components of therapeutics such as bispecific antibodies or...
Polyclonal Antibody Sequencing in Camelids

Polyclonal Antibody Sequencing in Camelids

Polyclonal Antibody Sequencing in Camelids Serum contains circulating antibodies with unique functional properties. This fundamental fact is why we choose to mine the serum over cells – despite being more challenging. Here we compare the two approaches for...
Monoclonal versus Polyclonal Antibody Sequencing

Monoclonal versus Polyclonal Antibody Sequencing

Monoclonal versus Polyclonal Antibody Sequencing Antibody reagents used in biomedical research and diagnostics assays fall into two large categories: monoclonals and polyclonals. For high-quality reagents, an antibody needs to demonstrate specific reactivity in its...