De Novo Antibody Sequencing Case Study
Abterra Bio uses bioinformatics and mass spectrometry to reconstructs the full amino acid sequence of both antibody chains. We’ve successfully sequenced human, mouse, rat, hamster, rabbit, and llama antibodies. This approach can be applied across any species and isotype, including IgG’s and IgM’s.
Contact us to learn more about how our Valens™ de novo antibody sequencing can recover the full antibody sequence when no source cell is available!
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For 100% sequence accuracy, antibody sequencing experience matters. Read our blog post to understand more about our service and why you would need de novo sequencing.
Polyclonal Antibody Sequencing Methods
Polyclonal Antibody Sequencing Methods Polyclonal antibody sequencing is a powerful tool for understanding the humoral immune response.1 Two primary approaches exist: Proteogenomic Polyclonal Antibody Sequencing and De Novo Polyclonal Antibody Sequencing. This guide...
Griffin: Accessing functional antibodies from serum without B cells
Griffin is a platform for sequencing polyclonal antibodies using mass spectrometry. Since 2009, Abterra Biosciences founders and employees have been developing novel methods for sequencing antibody proteins directly. Our monoclonal antibody sequencing service,...
Antibody Clonality Assessment
Antibody Clonality Background The serological compartment is simple to access and contains a multitude of proteins, a large fraction of which are circulating antibodies. At Abterra Bio, we developed Alicanto which utilizes B cells from a variety of sources, including...